I was able to put these boots on straight out of the box and do a 5 day backpacking trip in the canyons of the San Rafael Swell of Utah toting a 60lb pack with no blisters or foot pain at all (22 miles). I was surprised at the amount of support they provided while also being able to "feel" my foot placements while scrambling. The heel of the boot has a unique shape that works very well for steep descents as it grips tight and naturally rolls your foot forward. I had no issues with getting these boots on or off, you just have to understand your foot is in a bootie inside a shell and use the loops accordingly. I did find removing the liner was a convenient way to get them to dry faster (from sweat).
The only concern I have with the liner concept is the lacing portion of the boot is exposed, so stepping into a weak ice puddle allows water to enter the boot and get between the liner and the boot shell. This is not an issue with normal boots that have a tongue to seal your foot off. With that said, if I know I will be hiking through water hazards, I will wear gators (which fit very well on these boots).
They are pricey, but I am happy with the money spent, I just hope they stand up to the test of time like the 10 years I got from my last pair of Asolos.