I usually hike in trail running shoes (lately Brooks Cascadia 11), but for big days with a pack or crampon-questionable outings (yes, strap-ons work, but don't get any ideas about technical footwork), these things are amazing. They're light but supportive and feel great all day -- you might even jog that last mile to the car. The e-vent is good for snow and stream crossings but it does keep your feet toasty. I do a sock swap at lunch to keep the swampiness at bay.
As for sizing, I'm somewhere between a 12 and 12.5 and went with the 12s. They fit great, though I have pretty narrow feet. As for in-brand sizing, I've run in a few different Hokas and these fit and feel more like the Bondi than the ATR 2.