I first tried these boots on while traveling abroad and immediately fell in love. They were my first purchase when I returned home to the states! These boots were recommended to me based on my feet type (narrow-medium width, normal arches). A few thoughts:
Sizing - I ordered my normal size (Women's 8) and they fit perfectly, with plenty of room in the toe box with medium-thickness wool socks. They are a bit more snug with thick backpacking socks but not enough to size up. If you're unsure of your size, I'd recommend ordering your street shoe size and a half size up, try them on at home, and return the pair that doesn't work. I'd also be cautious about buying these shoes if you have wide feet, as they do seem to run a bit narrow, but Lowa does make the renegades in a wide width.
Break-in period - As other adventurers have reported, these shoes were comfortable right out of the box! I have a lot of trouble finding hiking boots that fit well, as my heels tend to slip/slide against the back of the boot as I walk, giving me horrible blisters. Not in the Renegades! After a moderate 11-mile hike in Big Basin this past weekend, I'm happy to report that I had zero hot spots or blisters!
Durability - I've only used them a few times, so I'll have to report on the longevity of these boots, but so far so good!
Comfort - While these boots are incredibly comfortable right out of the box, I would suggest replacing the insoles if you're going to be using them for anything other than moderate day hikes (<7 miles). Toward the end of my 11-mile journey, my feet were beginning to feel a bit strained. I'll definitely be slipping my Green Superfeet into these boots next time I head into the backcountry for added comfort/support, especially if I decide to use them while backpacking.