Background: I am 215 lbs, ride about 75-100 miles a week, and ride an Allez Smartweld with custom built wheels with DT Swiss RR440 tubeless ready rims. They are sort of a budget, stiff, bomb-proof wheel set.
I previously ran through two sets of Krylions in 23mm. I was impressed with the rolling resistance, grip, and durability (I flatted twice in 6,000 miles, both due to pinch. When it came time to replace them, I decided to give another Michelin tire a go, and Competitive Cyclist had a great price I could not pass up.
It is my understanding that the Pro4 Endurance is essentially the newer generation of Krylion, and so far I've found it to be far superior to that tire. The 25mm width results in a drastically improved ride. My bike is much more comfortable. I would run my 23mm Krylion in 100F/110R PSI, I run these Pro4 Endurance at 95F/105R. The grip is also leaps and bounds improved over the Krylion, and the rolling resistance is a little improved.
The biggest negative is that these were a PAIN to mount on my RR440 rims. Its probably due to those being tubeless ready. Just something to be aware of if you are running clinchers on your tubeless rims.
I'll update the review with longevity impressions later. If I get ~2,500 miles out of the rears, I will be very happy as this is what I got with the Krylion.