Brenden G.wrote a review of La Sportiva Mutant Running Shoe - Men's on July 26, 2018
Familiarity: I've put it through the wringer
Fit: True to size
This has been my go-to shoe for most things mountain in the past year. Used in a variety of Colorado locations - Boulder foothills, Elk and San Juan mountains, etc. I have worn them in all sorts of conditions - dry, wet, rainy, snowy, sloppy, rocky - and feel comfortable in most. I definitely take these out in adverse conditions more so than other shoes (e.g. Hoka Challenger).
The sticky rubber works fantastically. Lugs are solid and grippy and have held up for 400-500 miles. With their depth it can feel a little uneasy scrabbling up steep slabs (e.g. Flatirons in Boulder) as the lugs shift a little until they "set", but the stickiness of the rubber balances it out.
Shoe is softer than an approach shoe, but firmer and more rigid than many lightweight neutral running shoes.
Occasionally I would feel a little rubbing on the outside bottom side of my ankle from the top of the upper, but I just wore them for five days of mostly off-trail backpacking in the San Juan Mountains of Colorado with no problems.
The side lacing system took a little while to get used to, but it keeps the lacing fairly snug with the z pattern (getting the lower laces snug toward the toes is a little tricky as the lace doesn't hold super tight down there, but it has never felt sloppy or loose regardless). The lace tuck-in stash on the side of the tongue is great as well - keeps them out of the way, and probably keeps them tied better!
Shoes have taken a beating and the only major signs of wear are a small delaminating around the toe cap (which happened because I snagged it on a root), and a little blowout near the pinky toe (took 400+ miles though).
I have worn 45s in the Wildcats, and 45.5 in the Helios and Vertical K. 45 in the Mutants fit me well.
Definitely recommend these as stable, sturdy mountain running shoes that are still pretty lightweight.