These were the first Ergon grips I tried. I do in fact have pretty large hands. I wear XL and even XXL gloves, so I tried the large size grips. They were fine riding on flat, open bike paths etc, but riding on single track trails, I felt like I was wearing mittens or something. I don't think it really matters how big your hands are, these just are not designed with bike handling in mind. If you intend any off road, technical use, try a different model like the GS1 or GX1. If you just plan on cruising around the neighborhood and such, these will be fine.