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I became a fan of compression socks in general after some nurse friends told me they use the compression socks for long work days on their feet, so I started out using them when I worked standing on my feet in retail/service industry full time. So it only made sense to me to try these out for running and backpack/hiking trips. Because they are compressive it is a little tricky getting them on, but once on they feel obviously compressive, but not suffocating or too tight. Its honestly hard to tell whether they make a huge difference compared to backpacking without them because no matter what you are wearing, hiking 15+ miles in a day while wearing 20-30+ lbs in mostly 10,000 ft elevation, your legs are going to feel tired no matter what. Still, I think these come in handy when you are being active on your feet often and I will probably continue using them for my outdoor pursuits. I can usually wear these a few days at a time before they get really stinky. For ladies concerned with future bluging varicose veins on their legs, compression socks are supposed to help prevent or reduce them!